BAIT
TMED10
1110014C03Rik, Tmp21, p23, p24delta1
transmembrane emp24-like trafficking protein 10 (yeast)
GO Process (5)
GO Function (2)
GO Component (15)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- COPI-coated vesicle [ISO]
- Golgi apparatus [ISO]
- Golgi membrane [ISO]
- cell [TAS]
- cis-Golgi network [ISO, ISS]
- endoplasmic reticulum [ISO]
- endoplasmic reticulum-Golgi intermediate compartment [ISO]
- extracellular vesicular exosome [ISO]
- gamma-secretase complex [ISO]
- integral component of membrane [ISO]
- intracellular [TAS]
- intracellular membrane-bounded organelle [ISO]
- plasma membrane [ISO]
- secretory granule membrane [IDA]
- zymogen granule membrane [IDA, ISO]
Mus musculus
PREY
TPM1
C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA
tropomyosin 1 (alpha)
GO Process (17)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- cardiac muscle contraction [IMP]
- cellular component movement [TAS]
- cellular response to reactive oxygen species [IEP]
- cytoskeleton organization [TAS]
- muscle contraction [TAS]
- muscle filament sliding [ISS, TAS]
- negative regulation of cell migration [ISS]
- positive regulation of ATPase activity [ISS]
- positive regulation of cell adhesion [ISS]
- positive regulation of heart rate by epinephrine [ISS]
- positive regulation of stress fiber assembly [ISS]
- regulation of heart contraction [TAS]
- regulation of muscle contraction [TAS]
- ruffle organization [ISS]
- sarcomere organization [IMP]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- wound healing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID