BAIT
CD2AP
AL024079, C78928, METS-1, Mets1
CD2-associated protein
GO Process (8)
GO Function (7)
GO Component (12)
Gene Ontology Biological Process
- cell migration [ISO]
- negative regulation of transforming growth factor beta1 production [IGI]
- positive regulation of protein localization to nucleus [IGI]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISO]
- regulation of actin cytoskeleton reorganization [IGI]
- regulation of receptor-mediated endocytosis [ISO]
- single organismal cell-cell adhesion [ISO]
- vesicle organization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
IFRD2
IFNRP, SKMc15, SM15
interferon-related developmental regulator 2
GO Process (0)
GO Function (1)
GO Component (1)
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID