BAIT
UBR5
Edd, Edd1
ubiquitin protein ligase E3 component n-recognin 5
GO Process (9)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [ISO]
- negative regulation of double-strand break repair [ISO]
- negative regulation of histone H2A K63-linked ubiquitination [ISO]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of catenin import into nucleus [ISO]
- positive regulation of protein import into nucleus, translocation [ISO]
- progesterone receptor signaling pathway [IBA, ISO]
- protein polyubiquitination [ISO]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA]
Gene Ontology Molecular Function
Mus musculus
PREY
KCNAB2
AKR6A5, HKvbeta2, HKvbeta2.1, HKvbeta2.2, KCNA2B, KV-BETA-2, RP1-233K16.1
potassium voltage-gated channel, shaker-related subfamily, beta member 2
GO Process (1)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID