BAIT
MAD2L2
2310033C13Rik, G1-453-4, MAD2B, REV7, repro22, RP23-139J21.8
MAD2 mitotic arrest deficient-like 2
GO Process (15)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- DNA damage response, signal transduction resulting in transcription [ISO]
- actin filament organization [ISO]
- double-strand break repair [ISO]
- negative regulation of canonical Wnt signaling pathway [ISO]
- negative regulation of cell-cell adhesion mediated by cadherin [ISO]
- negative regulation of epithelial to mesenchymal transition [ISO]
- negative regulation of mitotic anaphase-promoting complex activity [ISO]
- negative regulation of protein catabolic process [ISO]
- negative regulation of sequence-specific DNA binding transcription factor activity [ISO]
- negative regulation of transcription by competitive promoter binding [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription regulatory region DNA binding [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of cell growth [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BANF1
BAF, BCRP1, D14S1460, NGPS
barrier to autointegration factor 1
GO Process (6)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID