BAIT
HAX1
HAX-1, HSP1BP-1, Hs1bp1, SIG-111, Silg111, mHAX-1s
HCLS1 associated X-1
GO Process (10)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- cell surface receptor signaling pathway [TAS]
- cellular response to cytokine stimulus [ISO]
- positive regulation of actin cytoskeleton reorganization [ISO]
- positive regulation of granulocyte differentiation [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of actin filament polymerization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
KIF3B
FLA8, HH0048, KLP-11
kinesin family member 3B
GO Process (13)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- anterograde axon cargo transport [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- cytoskeleton-dependent intracellular transport [IBA]
- determination of left/right symmetry [TAS]
- membrane organization [TAS]
- metabolic process [IBA, TAS]
- microtubule-based movement [IBA, TAS]
- mitotic centrosome separation [TAS]
- mitotic spindle organization [TAS]
- plus-end-directed vesicle transport along microtubule [TAS]
- spindle assembly involved in mitosis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID