BAIT
CDK1
Cdc2, Cdc2a, p34
cyclin-dependent kinase 1
GO Process (18)
GO Function (8)
GO Component (8)
Gene Ontology Biological Process
- cell aging [ISO]
- chromosome condensation [ISO]
- histone phosphorylation [ISO]
- mitotic G2 DNA damage checkpoint [IDA]
- negative regulation of apoptotic process [ISO]
- organ regeneration [ISO]
- peptidyl-serine phosphorylation [ISO]
- peptidyl-threonine phosphorylation [ISO]
- positive regulation of DNA replication [ISO]
- positive regulation of cardiac muscle cell proliferation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of mitotic cell cycle [ISO]
- positive regulation of protein import into nucleus, translocation [ISO]
- protein complex assembly [ISO]
- protein localization to kinetochore [ISO]
- protein phosphorylation [IDA]
- response to ethanol [ISO]
- response to organonitrogen compound [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SEC24C
SEC24 family member C
GO Process (9)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- COPII vesicle coating [TAS]
- ER to Golgi vesicle-mediated transport [NAS, TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cellular protein metabolic process [TAS]
- membrane organization [TAS]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID