BAIT
CYR61
AI325051, CCN1, Igfbp10
cysteine rich protein 61
GO Process (33)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- apoptotic process involved in heart morphogenesis [IMP]
- atrial septum morphogenesis [IMP]
- atrioventricular valve morphogenesis [IMP]
- cell adhesion [IDA, ISO]
- cell-cell signaling [IBA]
- chemotaxis [ISO]
- chondroblast differentiation [IDA]
- chorio-allantoic fusion [IMP]
- extracellular matrix organization [IDA]
- intussusceptive angiogenesis [IMP]
- labyrinthine layer blood vessel development [IMP]
- negative regulation of apoptotic process [IMP]
- osteoblast differentiation [IGI]
- positive regulation of BMP signaling pathway [ISO]
- positive regulation of apoptotic process [IGI]
- positive regulation of cartilage development [IMP]
- positive regulation of cell differentiation [IDA]
- positive regulation of cell migration [IDA, ISO]
- positive regulation of cell-substrate adhesion [IDA]
- positive regulation of ceramide biosynthetic process [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IGI]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of osteoblast proliferation [ISO]
- positive regulation of phospholipase activity [IDA]
- positive regulation of protein kinase activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- reactive oxygen species metabolic process [IDA]
- regulation of ERK1 and ERK2 cascade [ISO]
- signal transduction [IBA]
- single organismal cell-cell adhesion [IDA]
- ventricular septum development [IMP]
- wound healing, spreading of cells [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SRGAP3
ARHGAP14, MEGAP, SRGAP2, WRP
SLIT-ROBO Rho GTPase activating protein 3
GO Process (2)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID