BAIT
PAPSS1
AI325286, Asapk, SK1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
GO Process (3)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CASP8AP2
CED-4, FLASH, RIP25, RP11-63K6.3
caspase 8 associated protein 2
GO Process (7)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- Fas signaling pathway [IMP]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IMP, ISS]
- apoptotic signaling pathway [TAS]
- cellular response to mechanical stimulus [IEP]
- extrinsic apoptotic signaling pathway via death domain receptors [IMP, ISS]
- negative regulation of nucleic acid-templated transcription [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID