BAIT
KIF1B
A530096N05Rik, AI448212, AI506502, D4Mil1e, KIF1Bp130, KIF1Bp204, RP23-249G3.1
kinesin family member 1B
GO Process (9)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- anterograde axon cargo transport [IMP]
- cytoskeleton-dependent intracellular transport [IDA]
- embryo development [NAS]
- microtubule-based movement [IDA]
- mitochondrion transport along microtubule [IDA]
- neuromuscular synaptic transmission [IMP]
- neuron-neuron synaptic transmission [IMP]
- vesicle-mediated transport [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAD50
NBSLD, RAD502, hRad50
RAD50 homolog (S. cerevisiae)
GO Process (14)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IDA]
- DNA duplex unwinding [IMP]
- DNA recombination [IDA]
- DNA repair [IDA, TAS]
- cellular response to DNA damage stimulus [IDA]
- double-strand break repair [IMP, TAS]
- double-strand break repair via homologous recombination [TAS]
- nucleic acid phosphodiester bond hydrolysis [IDA]
- positive regulation of kinase activity [IDA]
- positive regulation of protein autophosphorylation [IDA]
- reciprocal meiotic recombination [TAS]
- regulation of mitotic recombination [IDA]
- telomere maintenance [TAS]
- telomere maintenance via telomerase [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID