BAIT
BMPR1A
1110037I22Rik, ALK3, AU045487, BMPR-IA, Bmpr
bone morphogenetic protein receptor, type 1A
GO Process (50)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- BMP signaling pathway [IDA, IGI, IMP, ISO]
- Mullerian duct regression [IMP]
- anterior/posterior pattern specification [IMP]
- cartilage development [IMP]
- cell differentiation [IGI]
- developmental growth [IMP]
- dorsal/ventral axis specification [IMP]
- dorsal/ventral pattern formation [IGI]
- ectoderm development [IMP]
- embryonic digit morphogenesis [IGI]
- embryonic morphogenesis [IMP]
- embryonic organ development [IMP]
- endocardial cushion formation [IMP]
- endoderm development [IMP]
- heart development [IMP]
- heart formation [IMP]
- heart morphogenesis [IMP]
- hindlimb morphogenesis [IMP]
- immune response [ISO]
- in utero embryonic development [IMP]
- lateral mesoderm development [IMP]
- lung development [IMP]
- mesendoderm development [IMP]
- mesoderm formation [IMP]
- negative regulation of neurogenesis [IMP]
- nervous system development [IMP]
- neural crest cell development [IMP]
- neural plate mediolateral regionalization [IMP]
- neural plate pattern specification [IMP]
- odontogenesis of dentin-containing tooth [IMP]
- palate development [IMP]
- paraxial mesoderm development [IGI, IMP]
- paraxial mesoderm structural organization [IMP]
- pattern specification process [IMP]
- pituitary gland development [IMP]
- positive regulation of SMAD protein import into nucleus [ISO]
- positive regulation of bone mineralization [ISO]
- positive regulation of epithelial cell proliferation [IMP]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [ISO]
- positive regulation of transcription, DNA-templated [IDA]
- protein phosphorylation [ISO]
- regulation of cellular senescence [IGI]
- regulation of endothelial cell differentiation [IDA]
- regulation of endothelial cell proliferation [IDA]
- regulation of lateral mesodermal cell fate specification [IGI]
- somitogenesis [IMP]
- stem cell maintenance [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
STUB1
CHIP, HSPABP2, NY-CO-7, SCAR16, SDCCAG7, UBOX1, LA16c-313D11.6
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
GO Process (15)
GO Function (15)
GO Component (10)
Gene Ontology Biological Process
- cellular response to misfolded protein [IDA]
- misfolded or incompletely synthesized protein catabolic process [IDA]
- negative regulation of transforming growth factor beta receptor signaling pathway [TAS]
- positive regulation of chaperone-mediated protein complex assembly [IDA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IDA]
- positive regulation of protein ubiquitination [IDA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- protein K63-linked ubiquitination [IDA]
- protein autoubiquitination [IDA]
- protein maturation [TAS]
- protein polyubiquitination [IDA, IMP]
- regulation of glucocorticoid metabolic process [IDA]
- transforming growth factor beta receptor signaling pathway [TAS]
- ubiquitin-dependent SMAD protein catabolic process [IDA]
- ubiquitin-dependent protein catabolic process [IMP]
Gene Ontology Molecular Function- G-protein coupled receptor binding [IPI]
- Hsp70 protein binding [IDA]
- Hsp90 protein binding [IDA]
- SMAD binding [IDA]
- TPR domain binding [IDA]
- enzyme binding [IPI]
- kinase binding [IPI]
- misfolded protein binding [IDA]
- protein binding [IPI]
- protein binding, bridging [TAS]
- protein homodimerization activity [ISS]
- ubiquitin protein ligase activity [IDA]
- ubiquitin protein ligase binding [IPI]
- ubiquitin-protein transferase activity [IDA, IMP, TAS]
- ubiquitin-ubiquitin ligase activity [ISS]
- G-protein coupled receptor binding [IPI]
- Hsp70 protein binding [IDA]
- Hsp90 protein binding [IDA]
- SMAD binding [IDA]
- TPR domain binding [IDA]
- enzyme binding [IPI]
- kinase binding [IPI]
- misfolded protein binding [IDA]
- protein binding [IPI]
- protein binding, bridging [TAS]
- protein homodimerization activity [ISS]
- ubiquitin protein ligase activity [IDA]
- ubiquitin protein ligase binding [IPI]
- ubiquitin-protein transferase activity [IDA, IMP, TAS]
- ubiquitin-ubiquitin ligase activity [ISS]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID