BAIT
MAD2L1
AA673185, MAD2
MAD2 mitotic arrest deficient-like 1
GO Process (9)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
- mitotic cell cycle checkpoint [ISO]
- mitotic sister chromatid segregation [IMP]
- mitotic spindle assembly checkpoint [IMP, ISA]
- negative regulation of apoptotic process [IMP, ISO]
- negative regulation of mitotic anaphase-promoting complex activity [ISO]
- negative regulation of mitotic cell cycle [ISO]
- negative regulation of mitotic metaphase/anaphase transition [TAS]
- negative regulation of protein catabolic process [ISO]
- positive regulation of mitotic cell cycle spindle assembly checkpoint [IMP, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
TUBB3
CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
tubulin, beta 3 class III
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID