BAIT
TPM1
AA986836, AI854628, TM2, Tm3, Tmpa, Tpm-1, alpha-TM
tropomyosin 1, alpha
GO Process (14)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
- actin filament capping [ISO]
- cardiac muscle contraction [IMP, ISO]
- embryo development [IMP]
- in utero embryonic development [IMP]
- muscle filament sliding [ISO]
- negative regulation of cell migration [ISO]
- positive regulation of ATPase activity [ISO]
- positive regulation of cell adhesion [ISO]
- positive regulation of heart rate by epinephrine [IMP]
- positive regulation of stress fiber assembly [ISO]
- regulation of ATPase activity [ISO]
- ruffle organization [ISO]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- wound healing [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BASP1
CAP-23, CAP23, NAP-22, NAP22
brain abundant, membrane attached signal protein 1
GO Process (10)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- diaphragm development [ISS]
- glomerular visceral epithelial cell differentiation [ISS]
- gonad development [ISS]
- mesenchymal to epithelial transition [ISS]
- metanephric mesenchyme development [ISS]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of heart growth [ISS]
- positive regulation of metanephric ureteric bud development [ISS]
- substantia nigra development [IEP]
- thorax and anterior abdomen determination [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID