BAIT
NHSL1
5730409E15Rik, A630035H13Rik, A730096F01, BC013565, D10Bwg0940e, mKIAA1357
NHS-like 1
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
NCKAP1
HEM2, NAP1, NAP125, p125Nap1
NCK-associated protein 1
GO Process (7)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- Rac protein signal transduction [IDA]
- apoptotic process [TAS]
- central nervous system development [TAS]
- innate immune response [TAS]
- positive regulation of Arp2/3 complex-mediated actin nucleation [IDA]
- positive regulation of lamellipodium assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID