BAIT
MSN
C78546, RP23-98K7.1
moesin
GO Process (3)
GO Function (5)
GO Component (21)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [ISO]
- apical part of cell [IDA, ISO]
- apical plasma membrane [IDA]
- basolateral plasma membrane [IDA]
- blood microparticle [ISO]
- cell periphery [ISO]
- cell surface [ISO]
- cell tip [ISO]
- cytoplasm [ISO]
- cytoplasmic side of plasma membrane [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- filopodium [ISO]
- filopodium membrane [ISO]
- focal adhesion [ISO]
- microvillus [ISO]
- myelin sheath [IDA]
- plasma membrane [ISO]
- secretory granule membrane [ISO]
- uropod [IDA]
- vesicle [ISO]
Mus musculus
PREY
PRDX3
AOP-1, AOP1, HBC189, MER5, PRO1748, SP-22, prx-III
peroxiredoxin 3
GO Process (15)
GO Function (7)
GO Component (7)
Gene Ontology Biological Process
- cellular response to oxidative stress [IDA]
- cellular response to reactive oxygen species [IMP]
- hydrogen peroxide catabolic process [IGI, IMP]
- mitochondrion organization [IMP]
- myeloid cell differentiation [ISS]
- negative regulation of apoptotic process [IDA, IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of kinase activity [IDA]
- peptidyl-cysteine oxidation [IDA]
- positive regulation of NF-kappaB transcription factor activity [IDA]
- positive regulation of cell proliferation [IDA]
- regulation of mitochondrial membrane potential [IMP]
- response to hydrogen peroxide [IDA]
- response to lipopolysaccharide [ISS]
- response to oxidative stress [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID