BAIT
IQGAP3
AI593484, D030034H08
IQ motif containing GTPase activating protein 3
GO Process (10)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- ERK1 and ERK2 cascade [IMP]
- G1/S transition of mitotic cell cycle [IMP]
- Ras protein signal transduction [IMP]
- activation of MAPK activity [IMP]
- cellular response to organic substance [IDA]
- negative regulation of gene expression [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of mammary gland epithelial cell proliferation [IMP]
- positive regulation of protein phosphorylation [IMP]
- regulation of cell size [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
COG2
LDLC, RP11-543E8.3
component of oligomeric golgi complex 2
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID