BAIT
CHMP4B
2010012F05Rik, C76846, Snf7-2, RP23-29D15.3
charged multivesicular body protein 4B
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- negative regulation of autophagic vacuole assembly [ISO]
- negative regulation of neuron death [ISO]
- positive regulation of viral release from host cell [ISO]
- posttranslational protein targeting to membrane [ISO]
- protein homooligomerization [ISO]
- regulation of viral process [ISO]
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [ISO]
- viral budding via host ESCRT complex [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RIMS1
CORD7, RAB3IP2, RIM, RIM1, RP5-1046G13.1
regulating synaptic membrane exocytosis 1
GO Process (14)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- calcium ion-dependent exocytosis [TAS]
- glutamate secretion [TAS]
- membrane fusion [NAS]
- neurotransmitter secretion [TAS]
- positive regulation of excitatory postsynaptic membrane potential [ISS]
- positive regulation of gene expression [ISS]
- positive regulation of inhibitory postsynaptic membrane potential [ISS]
- protein complex assembly [IDA]
- regulated secretory pathway [NAS]
- regulation of catalytic activity [TAS]
- regulation of neurotransmitter secretion [TAS]
- secretion [NAS]
- synaptic transmission [TAS]
- synaptic vesicle exocytosis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID