BAIT
SPRED2
C79158, RP23-223D13.1
sprouty-related, EVH1 domain containing 2
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- inactivation of MAPK activity [IMP]
- negative regulation of peptidyl-threonine phosphorylation [IDA, ISO]
- negative regulation of protein serine/threonine kinase activity [IDA]
- positive regulation of DNA damage response, signal transduction by p53 class mediator [IDA]
- regulation of protein deacetylation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MYCBP2
PAM, AC001226.5
MYC binding protein 2, E3 ubiquitin protein ligase
GO Process (0)
GO Function (1)
GO Component (1)
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID