BAIT
RASSF1
123F2, AA536941, AU044980, NORE2A, RDA32, REH3P21, Rassf1A, Rassf1B, Rassf1C, AL672219.1
Ras association (RalGDS/AF-6) domain family member 1
GO Process (6)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
WWC1
HBEBP3, HBEBP36, KIBRA, MEMRYQTL, PPP1R168
WW and C2 domain containing 1
GO Process (9)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- cell migration [IDA]
- establishment of cell polarity [TAS]
- hippo signaling [TAS]
- negative regulation of hippo signaling [IDA]
- negative regulation of organ growth [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of MAPK cascade [IDA]
- regulation of hippo signaling [IMP]
- regulation of intracellular transport [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID