BAIT
CNOT2
2600016M12Rik, 2810470K03Rik, AA537049, AA959607, AW557563, C79650
CCR4-NOT transcription complex, subunit 2
GO Process (6)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis, exonucleolytic [ISO]
- negative regulation of intracellular estrogen receptor signaling pathway [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of cytoplasmic mRNA processing body assembly [ISO]
- regulation of stem cell maintenance [IMP, ISO]
- trophectodermal cell differentiation [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
MACF1
ABP620, ACF7, MACF, OFC4
microtubule-actin crosslinking factor 1
GO Process (8)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- Golgi to plasma membrane protein transport [IDA]
- positive regulation of Wnt signaling pathway [ISS]
- positive regulation of axon extension [IDA]
- regulation of epithelial cell migration [ISS]
- regulation of focal adhesion assembly [ISS]
- regulation of microtubule-based process [IMP]
- wound healing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID