BAIT
USO1
115kDa, TAP, Vdp
USO1 vesicle docking factor
GO Process (5)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NPHP3
CFAP31, MKS7, NPH3, RHPD, RHPD1, SLSN3
nephronophthisis 3 (adolescent)
GO Process (19)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- atrial septum development [IMP]
- cilium morphogenesis [ISS]
- convergent extension involved in gastrulation [IGI]
- determination of intestine left/right asymmetry [IMP]
- determination of left/right symmetry [IMP]
- determination of liver left/right asymmetry [IMP]
- determination of pancreatic left/right asymmetry [IMP]
- determination of stomach left/right asymmetry [IMP]
- epithelial cilium movement involved in determination of left/right asymmetry [IC]
- heart looping [IMP]
- kidney development [IMP]
- kidney morphogenesis [IMP]
- lung development [IMP]
- maintenance of organ identity [IMP]
- negative regulation of canonical Wnt signaling pathway [IDA]
- photoreceptor cell maintenance [IMP]
- regulation of Wnt signaling pathway, planar cell polarity pathway [ISS]
- regulation of planar cell polarity pathway involved in neural tube closure [IC]
- ureter development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID