BAIT
SETD2
4921524K10Rik, BC031601, KMT3A
SET domain containing 2
GO Process (21)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- angiogenesis [IMP]
- cell migration involved in vasculogenesis [IMP]
- coronary vasculature morphogenesis [IMP]
- embryonic cranial skeleton morphogenesis [IMP]
- embryonic organ development [IMP]
- embryonic placenta morphogenesis [IMP]
- forebrain development [IMP]
- histone H3-K36 methylation [IMP]
- histone H3-K36 trimethylation [IMP, ISO]
- mesoderm morphogenesis [IMP]
- mismatch repair [ISO]
- morphogenesis of a branching structure [IMP]
- neural tube closure [IMP]
- nucleosome organization [ISO]
- peptidyl-lysine trimethylation [IMP]
- pericardium development [IMP]
- regulation of gene expression [IMP]
- regulation of mRNA export from nucleus [ISO]
- stem cell development [IMP]
- transcription elongation from RNA polymerase II promoter [ISO]
- vasculogenesis [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
PACSIN1
SDPI, RP11-375E1__A.1
protein kinase C and casein kinase substrate in neurons 1
GO Process (8)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
- cytoskeleton organization [IBA]
- establishment of protein localization to plasma membrane [ISS]
- membrane tubulation [IDA]
- neuron projection morphogenesis [IBA, ISS]
- positive regulation of dendrite development [ISS]
- protein localization to membrane [ISS]
- regulation of endocytosis [IBA]
- synaptic vesicle endocytosis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID