PAFAH1B1
Gene Ontology Biological Process
- acrosome assembly [IMP]
- actin cytoskeleton organization [IMP]
- adult locomotory behavior [IMP, ISO]
- ameboidal-type cell migration [IMP]
- brain morphogenesis [ISO]
- cell migration [IMP]
- cerebral cortex development [IGI, IMP, ISO]
- cerebral cortex neuron differentiation [ISO]
- corpus callosum morphogenesis [ISO]
- establishment of centrosome localization [ISO]
- establishment of mitotic spindle orientation [ISO]
- hippocampus development [IGI, IMP]
- layer formation in cerebral cortex [IGI]
- learning or memory [IMP]
- microtubule cytoskeleton organization [IGI, IMP]
- microtubule organizing center organization [ISO]
- microtubule-based process [ISO]
- negative regulation of JNK cascade [IGI]
- negative regulation of neuron projection development [ISO]
- neuroblast proliferation [IMP]
- neuromuscular process controlling balance [IMP, ISO]
- neuron migration [IGI, IMP, ISO]
- nuclear envelope disassembly [IMP]
- nuclear migration [ISO]
- osteoclast development [IMP]
- positive regulation of axon extension [ISO]
- positive regulation of cytokine-mediated signaling pathway [IMP]
- positive regulation of mitotic cell cycle [ISO]
- protein secretion [IMP]
- regulation of Rho GTPase activity [IMP]
- retrograde axon cargo transport [IDA]
- stem cell division [ISO]
- synaptic transmission [IMP]
- transmission of nerve impulse [IMP]
- vesicle transport along microtubule [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- astral microtubule [ISO]
- axon [ISO]
- cell [IGI]
- cell cortex [ISO]
- cell leading edge [IDA]
- centrosome [IDA, ISO]
- cytoplasm [IDA]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- intracellular [IGI]
- kinesin complex [ISO]
- kinetochore [ISO]
- microtubule associated complex [IDA, ISO]
- microtubule cytoskeleton [IDA]
- motile primary cilium [IDA]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nonmotile primary cilium [IDA]
- nuclear envelope [ISO, ISS]
- perinuclear region of cytoplasm [IDA]
- vesicle [ISO]
NDE1
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- cell migration [IBA]
- centrosome duplication [ISS]
- centrosome localization [IBA]
- cerebral cortex development [IMP]
- chromosome segregation [IBA]
- establishment of chromosome localization [IMP]
- establishment of mitotic spindle orientation [IMP]
- microtubule nucleation [IBA]
- mitotic cell cycle [TAS]
- mitotic centrosome separation [IBA]
- vesicle transport along microtubule [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PAFAH1B1 NDE1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID