BAIT
EIF3E
48kDa, Eif3s6, Int6, eIF3-p46, eIF3-p48
eukaryotic translation initiation factor 3, subunit E
GO Process (2)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
PHIP
BRWD2, DCAF14, WDR11, ndrp, RP11-173D14.2
pleckstrin homology domain interacting protein
GO Process (11)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- cytoskeleton organization [IMP]
- insulin receptor signaling pathway [NAS]
- negative regulation of apoptotic process [ISS]
- negative regulation of extrinsic apoptotic signaling pathway [IDA]
- positive regulation of cell proliferation [ISS]
- positive regulation of insulin-like growth factor receptor signaling pathway [ISS]
- positive regulation of mitosis [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [ISS]
- regulation of cell morphogenesis [IMP]
- regulation of protein phosphorylation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID