BAIT
TNPO1
AU021749, D13Ertd688e, IPO2, Kpnb2, MIP, MIP1, TRN
transportin 1
GO Process (0)
GO Function (2)
GO Component (1)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PCID2
F10, RP11-98F14.6
PCI domain containing 2
GO Process (6)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity [IMP]
- positive regulation of mitotic cell cycle spindle assembly checkpoint [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of mRNA stability [IMP]
- spleen development [ISS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID