BAIT
XPO1
AA420417, Crm1, Exp1, RP23-305E10.1
exportin 1, CRM1 homolog (yeast)
GO Process (8)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- protein export from nucleus [IDA, IMP, ISO]
- protein localization to nucleus [IMP]
- regulation of centrosome duplication [IMP]
- regulation of protein catabolic process [IMP]
- regulation of protein export from nucleus [IMP]
- ribosomal large subunit export from nucleus [ISO]
- ribosomal small subunit export from nucleus [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SCNM1
RP11-68I18.6
sodium channel modifier 1
GO Process (0)
GO Function (1)
GO Component (2)
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID