BAIT
RUVBL2
mp47, p47
RuvB-like protein 2
GO Process (12)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- cellular response to UV [ISO]
- cellular response to estradiol stimulus [ISO]
- chromatin remodeling [ISO]
- establishment of protein localization to chromatin [ISO]
- histone H2A acetylation [ISO]
- histone H4 acetylation [ISO]
- negative regulation of estrogen receptor binding [ISO]
- positive regulation of histone acetylation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- transcriptional activation by promoter-enhancer looping [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
EPC1
Epl1
enhancer of polycomb homolog 1 (Drosophila)
GO Process (9)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- chromatin organization [TAS]
- histone H2A acetylation [IDA]
- histone H4 acetylation [IDA]
- negative regulation of gene expression, epigenetic [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [TAS]
- transcription, DNA-templated [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID