BAIT
PCNA
RP23-33N15.1
proliferating cell nuclear antigen
GO Process (8)
GO Function (10)
GO Component (12)
Gene Ontology Biological Process
- base-excision repair, gap-filling [IDA]
- leading strand elongation [IBA]
- mismatch repair [IBA, ISO]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of deoxyribonuclease activity [ISO]
- regulation of catalytic activity [IBA]
- response to lipid [ISO]
- translesion synthesis [IBA, ISO]
Gene Ontology Molecular Function- DNA polymerase binding [ISO]
- DNA polymerase processivity factor activity [IBA]
- MutLalpha complex binding [ISO]
- dinucleotide insertion or deletion binding [ISO]
- estrogen receptor binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- purine-specific mismatch base pair DNA N-glycosylase activity [ISO]
- receptor tyrosine kinase binding [ISO]
- transcription factor binding [IPI]
- DNA polymerase binding [ISO]
- DNA polymerase processivity factor activity [IBA]
- MutLalpha complex binding [ISO]
- dinucleotide insertion or deletion binding [ISO]
- estrogen receptor binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- purine-specific mismatch base pair DNA N-glycosylase activity [ISO]
- receptor tyrosine kinase binding [ISO]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
Mus musculus
PREY
EPPK1
EPIPL, EPIPL1
epiplakin 1
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID