BAIT
ACTR1B
2310066K23Rik, AA960180, AI851923, Arp1b
ARP1 actin-related protein 1B, centractin beta
GO Process (0)
GO Function (0)
GO Component (4)
Gene Ontology Cellular Component
Mus musculus
PREY
OBSCN
ARHGEF30, UNC89, RP5-1139B12.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
GO Process (7)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- apoptotic signaling pathway [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of apoptotic process [TAS]
- protein localization to M-band [ISS]
- regulation of small GTPase mediated signal transduction [TAS]
- sarcomere organization [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID