BAIT
ECT2
AI528536, mKIAA4037
ect2 oncogene
GO Process (20)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- activation of Rac GTPase activity [ISO]
- activation of Rho GTPase activity [ISO]
- activation of protein kinase activity [ISO]
- cell morphogenesis [IDA]
- cellular response to calcium ion [ISO]
- cellular response to hydrogen peroxide [ISO]
- cellular response to ionizing radiation [ISO]
- cytokinesis [ISO]
- positive regulation of Cdc42 GTPase activity [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of Rho GTPase activity [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cytokinesis [ISO]
- positive regulation of neuron differentiation [IMP]
- positive regulation of protein import into nucleus [IDA]
- protein homooligomerization [ISO]
- regulation of attachment of spindle microtubules to kinetochore [ISO]
- regulation of protein kinase activity [ISO]
- signal transduction [ISO]
- tight junction assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PPP1R9B
PPP1R6, PPP1R9, SPINO, Spn
protein phosphatase 1, regulatory subunit 9B
GO Process (11)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- RNA splicing [NAS]
- cell cycle arrest [TAS]
- cell migration [IMP]
- cellular response to morphine [ISS]
- filopodium assembly [IMP]
- negative regulation of catalytic activity [NAS]
- negative regulation of cell growth [IDA]
- regulation of cell growth by extracellular stimulus [TAS]
- regulation of cell proliferation [NAS]
- regulation of exit from mitosis [NAS]
- regulation of opioid receptor signaling pathway [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID