BAIT
RPL35
2410039E09Rik, RP23-244N6.4
ribosomal protein L35
GO Process (0)
GO Function (1)
GO Component (3)
Gene Ontology Molecular Function
Mus musculus
PREY
DHX36
DDX36, G4R1, MLEL1, RHAU
DEAH (Asp-Glu-Ala-His) box polypeptide 36
GO Process (8)
GO Function (10)
GO Component (4)
Gene Ontology Biological Process
- ATP catabolic process [IBA, IDA]
- RNA processing [IBA]
- RNA secondary structure unwinding [IDA]
- innate immune response [TAS]
- ossification [ISS]
- positive regulation of telomere maintenance [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of type I interferon production [TAS]
Gene Ontology Molecular Function- ATP-dependent RNA helicase activity [IBA]
- DNA-dependent ATPase activity [IDA]
- G-quadruplex DNA binding [IDA]
- G-quadruplex RNA binding [IMP]
- core promoter binding [IDA]
- double-stranded RNA binding [IDA]
- histone deacetylase binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- transcription regulatory region DNA binding [ISS]
- ATP-dependent RNA helicase activity [IBA]
- DNA-dependent ATPase activity [IDA]
- G-quadruplex DNA binding [IDA]
- G-quadruplex RNA binding [IMP]
- core promoter binding [IDA]
- double-stranded RNA binding [IDA]
- histone deacetylase binding [ISS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- transcription regulatory region DNA binding [ISS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances.
The organization of a cell emerges from the interactions in protein networks. The interactome is critically dependent on the strengths of interactions and the cellular abundances of the connected proteins, both of which span orders of magnitude. However, these aspects have not yet been analyzed globally. Here, we have generated a library of HeLa cell lines expressing 1,125 GFP-tagged proteins ... [more]
Cell Oct. 22, 2015; 163(3);712-23 [Pubmed: 26496610]
Throughput
- High Throughput
Additional Notes
- interaction detected by quantitative BAC-GFP interactomics (QUBIC)
Curated By
- BioGRID