ARP4
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TAF14
Gene Ontology Biological Process
- RNA polymerase II transcriptional preinitiation complex assembly [IC]
- chromatin remodeling [IC]
- histone acetylation [IDA]
- nucleosome mobilization [IDA]
- promoter clearance from RNA polymerase II promoter [IC]
- transcription elongation from RNA polymerase II promoter [IC]
- transcription from RNA polymerase II promoter [IDA]
- transcription initiation from RNA polymerase II promoter [IDA]
- transcriptional start site selection at RNA polymerase II promoter [IC]
Gene Ontology Molecular Function- DNA translocase activity [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IC]
- core RNA polymerase II binding transcription factor activity [IDA]
- core RNA polymerase II recruiting transcription factor activity [IC]
- DNA translocase activity [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IC]
- core RNA polymerase II binding transcription factor activity [IDA]
- core RNA polymerase II recruiting transcription factor activity [IC]
Gene Ontology Cellular Component
- Ino80 complex [IDA, IPI]
- NuA3 histone acetyltransferase complex [IDA]
- NuA3a histone acetyltransferase complex [IDA]
- NuA3b histone acetyltransferase complex [IDA]
- SWI/SNF complex [IDA, IPI]
- mediator complex [IPI]
- nucleus [IDA]
- transcription factor TFIID complex [IDA]
- transcription factor TFIIF complex [IDA, IPI]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites.
Yeast histone H2A is phosphorylated on Ser129 upon DNA damage, an event required for efficient repair. We show that phosphorylation occurs rapidly over a large region around DNA double-strand breaks (DSBs). Histone H4 acetylation is also important for DSB repair, and we found that the NuA4 HAT complex associates specifically with phospho-H2A peptides. A single NuA4 subunit, Arp4, is responsible ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ARP4 TAF14 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| ARP4 TAF14 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 6 | BioGRID | 3604202 | |
| TAF14 ARP4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| TAF14 ARP4 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| ARP4 TAF14 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low/High | - | BioGRID | 284050 |
Curated By
- BioGRID