TUB2
Gene Ontology Biological Process
Gene Ontology Cellular Component
YCG1
Gene Ontology Biological Process
- meiotic chromosome condensation [IMP]
- meiotic chromosome separation [IMP]
- mitotic chromosome condensation [IGI, IMP]
- mitotic sister chromatid segregation [IMP]
- negative regulation of meiotic DNA double-strand break formation [IMP]
- rDNA condensation [IMP]
- synaptonemal complex assembly [IMP]
- tRNA gene clustering [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Structural maintenance of chromosome (SMC) proteins link microtubule stability to genome integrity.
Structural maintenance of chromosome (SMC) proteins are key organizers of chromosome architecture and are essential for genome integrity. They act by binding to chromatin and connecting distinct parts of chromosomes together. Interestingly, their potential role in providing connections between chromatin and the mitotic spindle has not been explored. Here, we show that yeast SMC proteins bind directly to microtubules and ... [more]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
TUB2 YCG1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.411 | BioGRID | 1931200 |
Curated By
- BioGRID