BAIT
RBPJ
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
recombination signal binding protein for immunoglobulin kappa J region
GO Process (28)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- DNA recombination [NAS]
- Notch signaling involved in heart development [IC]
- Notch signaling pathway [IMP, TAS]
- angiogenesis [ISS]
- atrioventricular canal development [ISS]
- blood vessel endothelial cell fate specification [ISS]
- blood vessel lumenization [ISS]
- cardiac left ventricle morphogenesis [ISS]
- dorsal aorta morphogenesis [ISS]
- endocardium morphogenesis [ISS]
- epithelial to mesenchymal transition [ISS]
- epithelial to mesenchymal transition involved in endocardial cushion formation [ISS]
- gene expression [TAS]
- labyrinthine layer blood vessel development [ISS]
- negative regulation of ossification [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISS]
- negative regulation of transcription, DNA-templated [IDA]
- outflow tract morphogenesis [ISS]
- positive regulation of BMP signaling pathway [ISS]
- positive regulation of ERBB signaling pathway [ISS]
- positive regulation of cardiac muscle cell proliferation [ISS]
- positive regulation of cell proliferation involved in heart morphogenesis [ISS]
- positive regulation of ephrin receptor signaling pathway [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription of Notch receptor target [IDA]
- regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [ISS]
- transcription initiation from RNA polymerase II promoter [TAS]
- ventricular trabecula myocardium morphogenesis [ISS]
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II repressing transcription factor binding [IPI]
- protein binding [IPI]
- recombinase activity [NAS]
- sequence-specific DNA binding transcription factor activity [TAS]
- DNA binding [TAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- RNA polymerase II repressing transcription factor binding [IPI]
- protein binding [IPI]
- recombinase activity [NAS]
- sequence-specific DNA binding transcription factor activity [TAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
RANGAP1
Fug1, RANGAP, SD, RP4-756G23.7
Ran GTPase activating protein 1
GO Process (3)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Curated By
- BioGRID