TCF4
Gene Ontology Biological Process
- DNA-templated transcription, initiation [ISS]
- positive regulation of neuron differentiation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [IDA]
- protein-DNA complex assembly [ISS]
- transcription initiation from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function- DNA binding [IDA]
- E-box binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISS]
- TFIIB-class binding transcription factor activity [ISS]
- TFIIB-class transcription factor binding [ISS]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [ISS, NAS]
- sequence-specific DNA binding RNA polymerase recruiting transcription factor activity [ISS]
- sequence-specific DNA binding transcription factor activity [IDA]
- DNA binding [IDA]
- E-box binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISS]
- TFIIB-class binding transcription factor activity [ISS]
- TFIIB-class transcription factor binding [ISS]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [ISS, NAS]
- sequence-specific DNA binding RNA polymerase recruiting transcription factor activity [ISS]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
RUNX1T1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TCF4 RUNX1T1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 2217890 | |
| TCF4 RUNX1T1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3115268 |
Curated By
- BioGRID