BAIT

FOXA2

HNF3B, TCF3B
forkhead box A2
GO Process (20)
GO Function (5)
GO Component (1)

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

Li X, Wang W, Wang J, Malovannaya A, Xi Y, Li W, Guerra R, Hawke DH, Qin J, Chen J

The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]

Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]

Throughput

  • High Throughput

Additional Notes

  • High-confidence interactions

Curated By

  • BioGRID