BAIT
FOXA2
HNF3B, TCF3B
forkhead box A2
GO Process (20)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- adult locomotory behavior [ISS]
- cell fate specification [ISS]
- dopaminergic neuron differentiation [ISS]
- endocrine pancreas development [IDA]
- negative regulation of detection of glucose [ISS]
- negative regulation of epithelial to mesenchymal transition [IMP]
- negative regulation of glucokinase activity [ISS]
- negative regulation of sequence-specific DNA binding transcription factor activity [IMP]
- negative regulation of transcription from RNA polymerase II promoter by glucose [ISS]
- positive regulation of cell-cell adhesion mediated by cadherin [IC]
- positive regulation of embryonic development [ISS]
- positive regulation of gastrulation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription from RNA polymerase II promoter by glucose [ISS]
- positive regulation of transcription, DNA-templated [IDA, ISS]
- primitive streak formation [ISS]
- regulation of blood coagulation [IDA]
- regulation of insulin secretion involved in cellular response to glucose stimulus [ISS]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to interleukin-6 [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
AGL
GDE
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
GO Process (4)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Curated By
- BioGRID