BAIT
FOXB1
FKH5, HFKH-5
forkhead box B1
GO Process (17)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- axon target recognition [ISS]
- cell migration in diencephalon [ISS]
- epithelial cell differentiation involved in mammary gland alveolus development [ISS]
- floor plate development [ISS]
- hypothalamus cell migration [ISS]
- inferior colliculus development [ISS]
- lactation [ISS]
- mammary gland lobule development [ISS]
- mammillary body development [ISS]
- mammillothalamic axonal tract development [ISS]
- midbrain development [ISS]
- negative regulation of neuron apoptotic process [ISS]
- regulation of transcription from RNA polymerase II promoter [IBA]
- somitogenesis [ISS]
- telencephalon cell migration [ISS]
- transcription from RNA polymerase II promoter [IBA]
- visual learning [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
KPNA1
IPOA5, NPI-1, RCH2, SRP1
karyopherin alpha 1 (importin alpha 5)
GO Process (10)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [TAS]
- apoptotic DNA fragmentation [TAS]
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- cytokine-mediated signaling pathway [TAS]
- intracellular transport of virus [TAS]
- positive regulation of protein import into nucleus [ISS]
- regulation of DNA recombination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Curated By
- BioGRID