BAIT
FOXH1
FAST-1, FAST1
forkhead box H1
GO Process (7)
GO Function (13)
GO Component (5)
Gene Ontology Biological Process
- negative regulation of androgen receptor activity [IDA]
- negative regulation of androgen receptor signaling pathway [IDA]
- negative regulation of intracellular estrogen receptor signaling pathway [IDA]
- nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry [NAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- transforming growth factor beta receptor signaling pathway [ISS, TAS]
Gene Ontology Molecular Function- DNA binding [IDA]
- R-SMAD binding [IMP, IPI]
- SMAD binding [IPI]
- androgen receptor binding [IPI]
- bHLH transcription factor binding [IPI]
- co-SMAD binding [IMP]
- enhancer binding [IC]
- protein binding [IPI]
- protein domain specific binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- transcription regulatory region DNA binding [ISS]
- DNA binding [IDA]
- R-SMAD binding [IMP, IPI]
- SMAD binding [IPI]
- androgen receptor binding [IPI]
- bHLH transcription factor binding [IPI]
- co-SMAD binding [IMP]
- enhancer binding [IC]
- protein binding [IPI]
- protein domain specific binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- transcription regulatory region DNA binding [ISS]
Gene Ontology Cellular Component
Homo sapiens
PREY
ADAR
ADAR1, AGS6, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88DSRBP, P136, RP11-61L14.5
adenosine deaminase, RNA-specific
GO Process (15)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- adenosine to inosine editing [IDA, IMP, TAS]
- base conversion or substitution editing [IDA]
- cytokine-mediated signaling pathway [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- mRNA modification [TAS]
- miRNA loading onto RISC involved in gene silencing by miRNA [IDA]
- negative regulation of protein kinase activity by regulation of protein phosphorylation [IDA, IMP]
- positive regulation of viral genome replication [IDA, IMP]
- pre-miRNA processing [IDA]
- protein export from nucleus [IDA]
- protein import into nucleus [IDA]
- response to interferon-alpha [IDA]
- response to virus [IMP]
- type I interferon signaling pathway [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Curated By
- BioGRID