FOXK1
Gene Ontology Biological Process
Gene Ontology Molecular Function
ING2
Gene Ontology Biological Process
- chromatin modification [ISS]
- male germ-line stem cell asymmetric division [ISS]
- male meiosis I [ISS]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [TAS]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation of transforming growth factor beta receptor signaling pathway [IDA]
- regulation of cellular senescence [NAS]
- regulation of response to DNA damage stimulus [NAS]
- regulation of transcription, DNA-templated [IDA]
- seminiferous tubule development [ISS]
- signal transduction [TAS]
- sperm motility [ISS]
- spermatid development [ISS]
- spermatogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Throughput
- High Throughput
Additional Notes
- High-confidence interactions
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ING2 FOXK1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9974 | BioGRID | 3151576 |
Curated By
- BioGRID