BAIT
FOXL2
BPES, BPES1, PFRK, PINTO, POF3
forkhead box L2
GO Process (11)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- apoptotic DNA fragmentation [IMP]
- cell differentiation [NAS]
- extraocular skeletal muscle development [IMP]
- menstruation [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- ovarian follicle development [IMP, ISS]
- positive regulation of apoptotic process [IGI, IMP]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- positive regulation of transcription, DNA-templated [ISS]
- regulation of transcription from RNA polymerase II promoter [IBA]
- transcription from RNA polymerase II promoter [IBA]
Gene Ontology Molecular Function- DNA binding [IDA, TAS]
- cysteine-type endopeptidase regulator activity involved in apoptotic process [IMP]
- protein binding [IPI]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [ISS, NAS]
- ubiquitin conjugating enzyme binding [IPI]
- DNA binding [IDA, TAS]
- cysteine-type endopeptidase regulator activity involved in apoptotic process [IMP]
- protein binding [IPI]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [ISS, NAS]
- ubiquitin conjugating enzyme binding [IPI]
Homo sapiens
PREY
SRPK2
SFRSK2
SRSF protein kinase 2
GO Process (14)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- RNA splicing [IDA]
- angiogenesis [ISS]
- innate immune response [IC]
- intracellular signal transduction [IDA]
- negative regulation of viral genome replication [IDA]
- nuclear speck organization [ISS]
- positive regulation of cell cycle [ISS]
- positive regulation of cell proliferation [IDA]
- positive regulation of gene expression [ISS]
- positive regulation of neuron apoptotic process [ISS]
- positive regulation of viral genome replication [IDA]
- protein phosphorylation [IDA]
- regulation of mRNA splicing, via spliceosome [TAS]
- spliceosomal complex assembly [IDA]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Curated By
- BioGRID