BAIT
FOXP1
12CC4, QRF1, hFKH1B, HSPC215
forkhead box P1
GO Process (24)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- T follicular helper cell differentiation [ISS]
- chemokine (C-C motif) ligand 2 secretion [IDA]
- endothelial cell activation [IMP]
- interleukin-21 secretion [ISS]
- macrophage activation [IDA]
- monocyte activation [IDA]
- negative regulation of B cell apoptotic process [IDA]
- negative regulation of androgen receptor signaling pathway [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- osteoclast development [IDA]
- osteoclast differentiation [IDA]
- positive regulation of endothelial cell migration [IMP]
- positive regulation of smooth muscle cell proliferation [IMP]
- regulation of defense response to bacterium [IDA]
- regulation of endothelial tube morphogenesis [IMP]
- regulation of inflammatory response [IDA]
- regulation of interleukin-1 beta secretion [IDA]
- regulation of interleukin-12 secretion [IDA]
- regulation of macrophage colony-stimulating factor production [IDA]
- regulation of monocyte differentiation [IDA]
- regulation of transcription from RNA polymerase II promoter [IBA]
- regulation of tumor necrosis factor production [IDA]
- response to lipopolysaccharide [IDA]
- transcription from RNA polymerase II promoter [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA]
- nucleus [IDA]
Homo sapiens
PREY
MYH10
NMMHC-IIB, NMMHCB
myosin, heavy chain 10, non-muscle
GO Process (5)
GO Function (7)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Curated By
- BioGRID