BAIT
FOXP3
AIID, DIETER, IPEX, PIDX, XPID, JM2
forkhead box P3
GO Process (25)
GO Function (9)
GO Component (3)
Gene Ontology Biological Process
- T cell activation [IDA]
- T cell homeostasis [NAS]
- chromatin remodeling [NAS]
- negative regulation of CREB transcription factor activity [IDA]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of T cell cytokine production [IDA]
- negative regulation of T cell proliferation [IDA]
- negative regulation of activated T cell proliferation [NAS]
- negative regulation of cell proliferation [IDA]
- negative regulation of cytokine biosynthetic process [IDA]
- negative regulation of cytokine secretion [IDA]
- negative regulation of histone deacetylation [IGI]
- negative regulation of immune response [IDA]
- negative regulation of interferon-gamma production [IDA]
- negative regulation of interleukin-10 production [IDA]
- negative regulation of interleukin-2 biosynthetic process [IMP]
- negative regulation of interleukin-2 production [IDA]
- negative regulation of interleukin-4 production [IDA]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of histone acetylation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISS]
- regulation of transcription, DNA-templated [NAS]
- response to virus [IEP]
Gene Ontology Molecular Function- NF-kappaB binding [NAS]
- NFAT protein binding [IPI]
- histone acetyltransferase binding [IPI]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
- NF-kappaB binding [NAS]
- NFAT protein binding [IPI]
- histone acetyltransferase binding [IPI]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IBA]
- sequence-specific DNA binding transcription factor activity [IDA, NAS]
Homo sapiens
PREY
ADAR
ADAR1, AGS6, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, K88DSRBP, P136, RP11-61L14.5
adenosine deaminase, RNA-specific
GO Process (15)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- adenosine to inosine editing [IDA, IMP, TAS]
- base conversion or substitution editing [IDA]
- cytokine-mediated signaling pathway [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- mRNA modification [TAS]
- miRNA loading onto RISC involved in gene silencing by miRNA [IDA]
- negative regulation of protein kinase activity by regulation of protein phosphorylation [IDA, IMP]
- positive regulation of viral genome replication [IDA, IMP]
- pre-miRNA processing [IDA]
- protein export from nucleus [IDA]
- protein import into nucleus [IDA]
- response to interferon-alpha [IDA]
- response to virus [IMP]
- type I interferon signaling pathway [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
The current knowledge on how transcription factors (TFs), the ultimate targets and executors of cellular signalling pathways, are regulated by protein-protein interactions remains limited. Here, we performed proteomics analyses of soluble and chromatin-associated complexes of 56 TFs, including the targets of many signalling pathways involved in development and cancer, and 37 members of the Forkhead box (FOX) TF family. Using ... [more]
Mol. Syst. Biol. Jan. 01, 2015; 11(1);775 [Pubmed: 25609649]
Throughput
- High Throughput
Curated By
- BioGRID