EIF3F
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ADRA1B
Gene Ontology Biological Process
- adrenergic receptor signaling pathway [IGI, ISO]
- adult heart development [IGI]
- behavioral response to cocaine [IMP]
- blood vessel remodeling [IMP]
- cell growth [IGI]
- glucose homeostasis [IMP]
- locomotory behavior [IMP]
- negative regulation of Rho protein signal transduction [ISO]
- negative regulation of glycogen catabolic process [IMP]
- organ growth [IGI]
- positive regulation of MAPK cascade [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of glycogen catabolic process [IMP]
- positive regulation of heart rate by epinephrine-norepinephrine [IGI]
- positive regulation of the force of heart contraction by epinephrine-norepinephrine [IGI]
- response to amphetamine [IMP]
- response to hormone [ISO]
- response to morphine [IMP]
- response to steroid hormone [ISO]
- vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure [IMP]
- visual learning [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
The eukaryotic translation initiation factor 3f (eIF3f) interacts physically with the alpha 1B-adrenergic receptor and stimulates adrenoceptor activity.
eIF3f is a multifunctional protein capable of interacting with proteins involved in different cellular processes, such as protein synthesis, DNA repair, and viral mRNA edition. In human cells, eIF3f is related to cell cycle and proliferation, and its deregulation compromises cell viability.We here report that, in native conditions, eIF3f physically interacts with the alpha 1B-adrenergic receptor, a plasma membrane protein ... [more]
Throughput
- Low Throughput
Additional Notes
- Figure 2
Curated By
- BioGRID