BAIT
TRIM29
ATDC
tripartite motif containing 29
GO Process (1)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BASP1
CAP-23, CAP23, NAP-22, NAP22
brain abundant, membrane attached signal protein 1
GO Process (10)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- diaphragm development [ISS]
- glomerular visceral epithelial cell differentiation [ISS]
- gonad development [ISS]
- mesenchymal to epithelial transition [ISS]
- metanephric mesenchyme development [ISS]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- positive regulation of heart growth [ISS]
- positive regulation of metanephric ureteric bud development [ISS]
- substantia nigra development [IEP]
- thorax and anterior abdomen determination [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.
Induction of DNA damage by ionizing radiation (IR) and/or cytotoxic chemotherapy is an essential component of cancer therapy. The ataxia telangiectasia group D complementing gene (ATDC, also called TRIM29) is highly expressed in many malignancies. It participates in the DNA damage response downstream of ataxia telangiectasia-mutated (ATM) and p38/MK2 and promotes cell survival after IR. To elucidate the downstream mechanisms ... [more]
J. Biol. Chem. Nov. 06, 2015; 290(45);27146-57 [Pubmed: 26381412]
Throughput
- High Throughput
Curated By
- BioGRID