BAIT
MCM2
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
minichromosome maintenance complex component 2
GO Process (6)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RPS19
DBA, DBA1, S19
ribosomal protein S19
GO Process (26)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- erythrocyte differentiation [IMP]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- maturation of SSU-rRNA [IMP]
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- monocyte chemotaxis [IDA]
- negative regulation of respiratory burst involved in inflammatory response [IDA]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- nucleolus organization [IMP]
- positive regulation of cellular component movement [TAS]
- positive regulation of respiratory burst involved in inflammatory response [IDA]
- protein tetramerization [IDA]
- rRNA processing [IMP]
- response to extracellular stimulus [TAS]
- ribosomal small subunit assembly [IMP]
- ribosomal small subunit biogenesis [IMP]
- translation [IC, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.
The minichromosome maintenance complex (MCM) proteins are required for processive DNA replication and are a target of S-phase checkpoints. The eukaryotic MCM complex consists of six proteins (MCM2-7) that form a heterohexameric ring with DNA helicase activity, which is loaded on chromatin to form the pre-replication complex. Upon entry in S phase, the helicase is activated and opens the DNA ... [more]
Mol. Cell Proteomics Jul. 01, 2015; 14(7);2002-13 [Pubmed: 25963833]
Throughput
- High Throughput
Curated By
- BioGRID