BAIT
HSD17B10
17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, RP3-339A18.2
hydroxysteroid (17-beta) dehydrogenase 10
GO Process (4)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
A2M
A2mp
alpha-2-macroglobulin
GO Process (4)
GO Function (12)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function- calcium-dependent protein binding [ISO]
- endopeptidase inhibitor activity [ISO]
- enzyme binding [ISO]
- growth factor binding [ISO]
- interleukin-1 binding [ISO]
- interleukin-8 binding [ISO]
- peptidase inhibitor activity [TAS]
- protease binding [ISO]
- protein binding [IPI]
- receptor binding [ISO]
- serine-type endopeptidase inhibitor activity [ISO]
- tumor necrosis factor binding [ISO]
- calcium-dependent protein binding [ISO]
- endopeptidase inhibitor activity [ISO]
- enzyme binding [ISO]
- growth factor binding [ISO]
- interleukin-1 binding [ISO]
- interleukin-8 binding [ISO]
- peptidase inhibitor activity [TAS]
- protease binding [ISO]
- protein binding [IPI]
- receptor binding [ISO]
- serine-type endopeptidase inhibitor activity [ISO]
- tumor necrosis factor binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.
Proteins involved in mitochondrial metabolic pathways engage in functionally relevant multi-enzyme complexes. We previously described an interaction between short-chain 3-hydroxyacyl-coenzyme A dehydrogenase (SCHAD) and glutamate dehydrogenase (GDH) explaining the clinical phenotype of hyperinsulinism in SCHAD-deficient patients and adding SCHAD to the list of mitochondrial proteins capable of forming functional, multi-pathway complexes. In this work, we provide evidence of SCHAD's involvement ... [more]
PLoS ONE Apr. 13, 2012; 7(4);e35048 [Pubmed: 22496890]
Throughput
- Low Throughput
Curated By
- BioGRID