BAIT
UBA52
D8Ertd21e, Gm1863, Rps27a, Ubb, Ubc
ubiquitin A-52 residue ribosomal protein fusion product 1
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Mus musculus
PREY
WRNIP1
WHIP, bA420G6.2, RP11-420G6.2
Werner helicase interacting protein 1
GO Process (3)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Co-crystal Structure
Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.
Publication
A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.
The ubiquitin-binding zinc finger (UBZ) is a type of zinc-coordinating β-β-α fold domain found mainly in proteins involved in DNA repair and transcriptional regulation. Here, we report the crystal structure of the UBZ domain of Y-family DNA polymerase (pol) η and the crystal structure of the complex between the UBZ domain of Werner helicase-interacting protein 1 (WRNIP1) and ubiquitin, crystallized ... [more]
FEBS J. Jun. 01, 2016; 283(11);2004-17 [Pubmed: 27062441]
Throughput
- Low Throughput
Additional Notes
- #LPPI
- Likely protein-protein interaction
- Uba52 (ubiquitin)
Curated By
- BioGRID