BAIT

RAD51D

R51H3, Rad51l3, TRAD, RP23-169P3.1
RAD51 homolog D
Mus musculus
PREY

RNF138

2410015A17Rik, 2810480D20Rik, STRIN, Trif, Trif-d
ring finger protein 138
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

RNF138 interacts with RAD51D and is required for DNA interstrand crosslink repair and maintaining chromosome integrity.

Yard BD, Reilly NM, Bedenbaugh MK, Pittman DL

The RAD51 family is integral for homologous recombination (HR) mediated DNA repair and maintaining chromosome integrity. RAD51D, the fourth member of the family, is a known ovarian cancer susceptibility gene and required for the repair of interstrand crosslink DNA damage and preserving chromosomal stability. In this report, we describe the RNF138 E3 ubiquitin ligase that interacts with and ubiquitinates the ... [more]

DNA Repair (Amst.) Jun. 01, 2016; 42(0);82-93 [Pubmed: 27161866]

Throughput

  • Low Throughput

Curated By

  • BioGRID