HSD17B10
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ALAD
Gene Ontology Biological Process
- cellular response to interleukin-4 [IDA]
- heme biosynthetic process [IDA, ISO]
- protein homooligomerization [ISO]
- response to arsenic-containing substance [ISO]
- response to cadmium ion [ISO]
- response to drug [ISO]
- response to ethanol [ISO]
- response to metal ion [ISO]
- response to nutrient [ISO]
- response to organic substance [ISO]
- response to zinc ion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.
Proteins involved in mitochondrial metabolic pathways engage in functionally relevant multi-enzyme complexes. We previously described an interaction between short-chain 3-hydroxyacyl-coenzyme A dehydrogenase (SCHAD) and glutamate dehydrogenase (GDH) explaining the clinical phenotype of hyperinsulinism in SCHAD-deficient patients and adding SCHAD to the list of mitochondrial proteins capable of forming functional, multi-pathway complexes. In this work, we provide evidence of SCHAD's involvement ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HSD17B10 ALAD | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID