BAIT

SHANK3

AI841104, SHANK3c-3, SHANK3c-4, Shank3b
SH3/ankyrin domain gene 3
GO Process (33)
GO Function (9)
GO Component (10)

Gene Ontology Biological Process

Mus musculus
PREY

ERC2

6430531D06, CAST, CAST1/ERC2, D14Ertd171e, ELKS2alpha
ELKS/RAB6-interacting/CAST family member 2
GO Process (0)
GO Function (3)
GO Component (8)
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

Li J, Wilkinson B, Clementel VA, Hou J, O'Dell TJ, Coba MP

The postsynaptic site of neurons is composed of more than 1500 proteins arranged in protein-protein interaction complexes, the composition of which is modulated by protein phosphorylation through the actions of complex signaling networks. Components of these networks function as key regulators of synaptic plasticity, in particular hippocampal long-term potentiation (LTP). The postsynaptic density (PSD) is a complex multicomponent structure that ... [more]

Sci Signal Aug. 11, 2016; 9(440);rs8 [Pubmed: 27507650]

Throughput

  • High Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SHANK3 ERC2
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
2334033

Curated By

  • BioGRID